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ALFENTANIL
Generic Name: ALFENTANIL
ABSTRACT -
Alfentanil is an intravenous opioid used by trained clinicians for anaesthesia and procedural analgesia. Dosing is individualized according to procedure, co-medication, and patient risk.
DOSAGE -
Use the current locally approved prescribing information where a product is authorized. For investigational products, dose, route, schedule, premedication, and dose modifications must come only from the applicable clinical-trial protocol. No dose should be selected from this summary.
SIDE EFFECTS–
- Respiratory depression
- Low blood pressure
- Bradycardia
- Nausea or vomiting
- Muscle rigidity
- Sedation
ALLRGIC REACTIONS–
(These symptoms may indicate a serious allergic or infusion reaction and require medical attention.)
- Hives or a rapidly spreading rash
- Swelling of the face, lips, tongue, or throat
- Wheezing, breathing difficulty, or sudden dizziness
- Severe blistering, mucosal lesions, or anaphylaxis
DRUG INTERACTIONS–
- CNS depressants and alcohol increase respiratory depression
- CYP3A inhibitors may increase exposure
- Serotonergic medicines can increase serotonin-syndrome risk
PREAUTIONS–
- Continuous respiratory and cardiovascular monitoring is required
- Use caution in frail patients and hepatic disease
WARNINGS –
- Profound respiratory depression, chest-wall rigidity, dependence, and fatal overdose can occur
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