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DUVOGLUSTAT
Generic Name: DUVOGLUSTAT
ABSTRACT -
Duvoglustat is an iminosugar alpha-glucosidase inhibitor investigated as a pharmacological chaperone and metabolic disease agent, including Pompe disease research settings.ies.
DOSAGE -
No approved dosage. Oral investigational dosing is protocol-specific.
SIDE EEFECTS -
- Gastrointestinal symptoms
- Flatulence or diarrhea
- Abdominal discomfort
- Headache
- Laboratory abnormalities
ALLERGIC REACTIONS -
(These symptoms may indicate an allergic reaction and require medical attention.)
- Rash or urticaria
- Angioedema
- Bronchospasm
- Anaphylaxis (rare)
DRUG INTERACTIONS-
- Other alpha-glucosidase inhibitors may increase gastrointestinal effects
- Carbohydrate digestion/absorption interactions may alter glucose control
- Monitor with antidiabetic therapy
PREAUTONS–
- Monitor glucose and gastrointestinal tolerability
- Use caution in significant gastrointestinal disease
- Investigational use requires protocol oversight
WARNINGS –
- Not approved for routine clinical use
- Hypoglycemia management may require glucose rather than sucrose if alpha-glucosidase inhibition is significant
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