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ALOGLIPTIN
Generic Name: ALOGLIPTIN
ABSTRACT -
Alogliptin improves glucose-dependent incretin activity and is used with diet and exercise in selected adults with type 2 diabetes.
DOSAGE -
Use the current locally approved prescribing information where a product is authorized. For investigational products, dose, route, schedule, premedication, and dose modifications must come only from the applicable clinical-trial protocol. No dose should be selected from this summary.
SIDE EFFECTS–
- Upper respiratory symptoms
- Headache
- Hypoglycaemia with insulin or sulfonylurea
- Pancreatitis
- Joint pain
- Heart-failure worsening
ALLRGIC REACTIONS–
(These symptoms may indicate a serious allergic or infusion reaction and require medical attention.)
- Hives or a rapidly spreading rash
- Swelling of the face, lips, tongue, or throat
- Wheezing, breathing difficulty, or sudden dizziness
- Severe blistering, mucosal lesions, or anaphylaxis
DRUG INTERACTIONS–
- Insulin and sulfonylureas increase hypoglycaemia risk
- Dose adjustment is required in renal impairment rather than for most metabolic interactions
PREAUTIONS–
- Assess kidney function before and during treatment
- Monitor for pancreatitis and heart-failure symptoms
WARNINGS –
- Acute pancreatitis, severe hypersensitivity, liver injury, and bullous pemphigoid have been reported
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