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EDIVOXETINE
Generic Name: EDIVOXETINE
ABSTRACT -
Edivoxetine is a selective norepinephrine reuptake inhibitor investigated for psychiatric indications. Development status and indication support should be verified before use.
DOSAGE -
Oral dosing in studies is protocol-specific. Do not extrapolate from other norepinephrine reuptake inhibitors.
SIDE EEFECTS -
- Insomnia or somnolence
- Nausea or decreased appetite
- Dry mouth
- Increased heart rate or blood pressure
- Anxiety, agitation, or dizziness
ALLERGIC REACTIONS -
These symptoms may indicate an allergic reaction and require medical attention.
- Rash, urticaria, angioedema, bronchospasm, or anaphylaxis
DRUG INTERACTIONS-
- MAO inhibitors and other noradrenergic drugs may cause serious reactions
- Antidepressants, stimulants, or serotonergic agents require specialist review
- Alcohol and CNS-active drugs may worsen adverse effects
PREAUTONS–
- Assess blood pressure, heart rate, suicidality, bipolar disorder, seizure risk, and glaucoma/urinary retention risk
- Tapering may be required for CNS-active medicines
- Pregnancy safety is not established
WARNINGS –
- Monitor for suicidal ideation, manic activation, hypertension, and serotonin/noradrenergic toxicity
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