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AVANAFIL
Generic Name: AVANAFIL
ABSTRACT -
Avanafil is an oral small-molecule phosphodiesterase type 5 inhibitor used where approved for erectile dysfunction. Its molecular formula is C₂₃H₂₆ClN₇O₃. The chemical representation above shows the 2D skeletal structure.
This document is for structured API information only. It is not a prescribing guide. Clinical use, if any, must follow the approved local label, trial protocol, and specialist medical supervision.
DOSAGE -
- Dosage should be determined only by a qualified healthcare professional.
- Use only according to the approved local product label for the specific indication.
- Dose, duration, and monitoring requirements may differ by disease, organ function, age, and interacting medicines.
- Do not change, stop, or restart treatment without medical supervision.
SIDE EFFECTS-
Possible side effects and safety concerns include:
- Headache, flushing, nasal congestion, back pain, or dyspepsia
- Dizziness, visual symptoms, or palpitations
- Hypotension, especially with interacting vasodilators
- Priapism, although rare, is a medical emergency
- Sudden hearing or vision changes have been reported with PDE5 inhibitors
ALLERGIC REACTIONS -
Hypersensitivity to Avanafil or related compounds/products may occur. Symptoms may include:
- Immediate urticaria, itching, flushing, or generalized rash
- Facial, lip, tongue, or throat swelling
- Wheezing, chest tightness, or breathing difficulty
- Dizziness, fainting, severe hypotension, or collapse
- Anaphylaxis, although uncommon, requires emergency medical treatment
Important: Patients who develop an allergic reaction to Avanafil should seek immediate medical attention and inform all future healthcare providers of the allergy.
DRUG INTERACTIONS-
Avanafil may interact with certain medicines, biologics, vaccines, protocols, or clinical conditions. Caution is needed with:
- Nitrates are contraindicated because severe hypotension can occur.
- Alpha-blockers and antihypertensives may increase blood-pressure lowering.
- Strong CYP3A inhibitors may increase avanafil exposure.
- Alcohol may worsen dizziness or hypotension.
Patients should inform healthcare providers about all prescription medicines, over-the-counter medicines, herbal products, vaccines, and supplements they are using.
PREAUTIONS–
- Evaluate cardiovascular fitness for sexual activity before use.
- Use caution in severe cardiac disease, recent stroke or myocardial infarction, or uncontrolled blood pressure.
- Avoid use with other erectile-dysfunction therapies unless directed.
- Seek urgent care for erection lasting longer than 4 hours.
WARNINGS –
- Do not combine with nitrates or guanylate-cyclase stimulators.
- Sudden vision loss, hearing loss, chest pain, or priapism requires urgent medical attention.
- Use only under medical advice for patients with cardiovascular disease.
- Keep out of reach of children.
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