Filter By Category
Archives
Share on -
ALVIMOPAN
Generic Name: ALVIMOPAN
ABSTRACT -
Alvimopan is used in restricted perioperative settings to accelerate gastrointestinal recovery after selected bowel surgery. Use is limited by cardiovascular safety requirements and local programmes.
DOSAGE -
Use the current locally approved prescribing information where a product is authorized. For investigational products, dose, route, schedule, premedication, and dose modifications must come only from the applicable clinical-trial protocol. No dose should be selected from this summary.
SIDE EFFECTS–
- Dyspepsia
- Constipation
- Nausea
- Anaemia
- Low potassium
- Possible myocardial-infarction risk with long-term exposure
ALLRGIC REACTIONS–
(These symptoms may indicate a serious allergic or infusion reaction and require medical attention.)
- Hives or a rapidly spreading rash
- Swelling of the face, lips, tongue, or throat
- Wheezing, breathing difficulty, or sudden dizziness
- Severe blistering, mucosal lesions, or anaphylaxis
DRUG INTERACTIONS–
- Recent therapeutic opioid use can increase gastrointestinal adverse effects
- P-glycoprotein inhibitors may alter exposure
PREAUTIONS–
- Confirm eligibility and recent opioid exposure
- Use only for the approved short inpatient course
WARNINGS –
Long-term use is not permitted in restricted programmes because of cardiovascular risk
Share on -
. Developed by