Filter By Category
Archives
Share on -
AMFETAMINE
Generic Name: AMFETAMINE
ABSTRACT -
Amfetamine, commonly known as amphetamine, is a central nervous system stimulant used in selected formulations for attention-deficit/hyperactivity disorder and narcolepsy. It increases synaptic dopamine and norepinephrine signaling through transporter-mediated release and reuptake inhibition. It is a controlled medicine with important cardiovascular, psychiatric, growth, and misuse risks.
This document is for structured API information only. It is not a prescribing guide. Clinical use, if any, must follow the approved local label, trial protocol, and specialist medical supervision.
DOSAGE -
- Dosage should be determined only by a qualified healthcare professional.
- Dosing depends on salt form, formulation, indication, age, response, and local labeling.
- Treatment is usually started at a low dose and titrated carefully.
- Avoid late-day dosing when possible because insomnia is common.
SIDE EFFECTS–
Possible side effects and safety concerns include:
- Reduced appetite, weight loss, dry mouth, or abdominal pain
- Insomnia
- Headache
- Anxiety, irritability, agitation, or mood changes
- Increased heart rate or blood pressure
- Tics or worsening psychiatric symptoms in susceptible patients
- Growth suppression in children with long-term use may occur and requires monitoring.
ALLRGIC REACTIONS–
Hypersensitivity to Amfetamine or related compounds/products may occur. Symptoms may include:
- Rash
- Urticaria
- Angioedema
- Breathing difficulty
- Anaphylaxis
Important: Patients who develop an allergic reaction to Amfetamine should seek immediate medical attention and inform all future healthcare providers of the allergy.
DRUG INTERACTIONS–
Amfetamine may interact with certain medicines, vaccines, protocols, or clinical conditions. Caution is needed with:
- MAO inhibitors are contraindicated.
- Other stimulants and sympathomimetics increase cardiovascular risk.
- Serotonergic medicines may increase serotonin-syndrome risk.
- Urinary acidifying or alkalinizing agents can alter exposure.
- Antihypertensive, antipsychotic, anticonvulsant, and acid-suppressing regimens require review.
Patients should inform healthcare providers about all prescription medicines, over-the-counter medicines, herbal products, vaccines, and supplements they are using.
PREAUTIONS–
- Screen for cardiac disease, hypertension, psychiatric history, tics, seizures, and substance-use risk.
- Monitor blood pressure, pulse, appetite, sleep, mood, and growth in children.
- Use caution in bipolar disorder, psychosis history, seizure disorder, and severe anxiety.
- Pregnancy and lactation require specialist advice.
WARNINGS –
- High potential for abuse, misuse, dependence, and diversion.
- Serious cardiovascular events, psychosis, mania, aggression, and serotonin syndrome can occur.
- Do not abruptly change dosing without medical advice.
- Keep securely stored and out of reach of children.
Share on -
. Developed by