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Galidesivir
Generic Name: galidesivir
Small molecule nucleoside analogue antiviral; molecular formula C11H15N5O3; MW 265.27 g/mol
ABSTRACT
galidesivir is a small-molecule antiviral nucleoside analogue. It is designed to interfere with viral nucleic-acid synthesis after intracellular activation.
DOSAGE
Dose and route depend on virus, disease severity, renal function, and protocol or prescribing information. Hydration and renal monitoring may be required.
SIDE EFFECTS
- Nausea, vomiting, diarrhea, or headache
- Bone-marrow suppression with some nucleoside analogues
- Renal function changes
- Liver enzyme abnormalities
ALLERGIC REACTIONS
These symptoms may indicate an allergic or hypersensitivity reaction and require medical attention.
- Urticaria, generalized rash, or pruritus
- Angioedema of lips, tongue, throat, or face
- Bronchospasm, dyspnea, wheezing, or chest tightness
- Anaphylaxis or severe infusion/injection reaction
DRUG INTERACTIONS
- Nephrotoxic drugs may increase renal toxicity
- Myelosuppressive drugs may increase cytopenia risk
- Dose adjustment may be needed in renal impairment
- Avoid overlapping antivirals unless protocol-supported
PRECAUTIONS
- Monitor CBC, renal function, and liver function
- Counsel on reproductive risk when applicable
- Use infection-specific susceptibility and resistance information
- Adjust dose in renal dysfunction
WARNINGS
- Severe neutropenia, thrombocytopenia, anemia, renal toxicity, or embryo-fetal risk may occur with some agents
- Use only with disease-specific monitoring
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